Binding Sites for Insulators

Classes_of_Insulator_Binding_Sites (White project, White subgroup)

Clustering analysis of six different Drosophila Insulator data sets (Negre et al., PLoS Genetics, 6: e1000814, 2010) revealed two distinct classes of insulator binding sites (based on their patterns of overlapping binding sites): Class I consists of CP190, BEAF-32 and CTCF, Class II consists of Su(Hw) and Mod(mdg4). The data track shows the locations for both classes.

General Description

To classify the binding patterns of six different Drosophila insulator proteins, we used a bioinformatics approach and defined two non-overlapping categories of insulators.

Protocols

  1. Other Protocols: Insulator annotation

Sample Details

  1. Animals/Lines: Drosophila melanogaster

Related modENCODE submissions:


Release Date: 2010-01-15